Many of the outbreaks at recently opened schools have occurred in states with relatively low vaccination rates. … In a South Carolina school district, 126 students and 22 staff members tested positive for COVID-19 during the first week back at school, resulting in more than 600 students and seven staff members having to quarantine after coming in contact with those who were positive. … Throughout the state of Mississippi, roughly 1,000 students and teachers have tested positive for COVID-19, and nearly 5,000 are quarantined.