One of the most, if not the most significant, correlates of vaccine hesitancy is partisanship. Republicans are much less likely to report getting or intending to get the vaccine than independents and Democrats. … Another significant correlate of vaccine hesitancy is education. … "Americans without a college degree are much more likely than college graduates to be vaccine-hesitant, 31% to 12%." … most frequently given reason for not getting the vaccine is worry about side effects -- coupled with a generalized lack of trust in vaccines.