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Eligible people may pay as little as $5 per co-pay. Restrictions apply.
WHEN TO EXPECT RESULTS
Use the calculator below to see when you can find out whether you’ve been cured with EPCLUSA.
EPCLUSA requires just 12 weeks of treatment (for most people, only one pill, once a day). Your doctor will test you three months after your last pill.
*In three separate clinical studies with a combined total of 1558 patients with genotype 1–6 Hep C, with or without prior Hep C treatment, and with or without cirrhosis (compensated), who received either EPCLUSA, a different treatment regimen, or placebo, 98% (1015/1035) of all patients who received EPCLUSA once daily for 12 weeks were cured. These studies did not include patients with advanced cirrhosis (decompensated).†
†EPCLUSA with ribavirin is recommended for patients with advanced cirrhosis (decompensated).‡ If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.
‡Advanced cirrhosis (decompensated) is when the liver is extensively scarred and can no longer do its job effectively.
Important Safety Information
What is the most important information I should know about EPCLUSA?
EPCLUSA can cause serious side effects, including:
- Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA.
What should I tell my healthcare provider before taking EPCLUSA?
- Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection, liver problems other than hepatitis C infection, or a liver transplant; if you have kidney problems or, are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.
- Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EPCLUSA and certain other medicines may affect each other, or may cause side effects.
What are the possible side effects of EPCLUSA?
Serious side effects may also include:
- Slow heart rate (bradycardia): EPCLUSA, when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.
The most common side effects of EPCLUSA include headache and tiredness. The most common side effects of EPCLUSA when used with ribavirin in adults with decompensated cirrhosis are tiredness, low red blood cells, nausea, headache, trouble sleeping, and diarrhea.
Tell your healthcare provider if you have any side effect that bothers you or does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
What is EPCLUSA?
EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin.
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